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【TED】青少年科学家发明的帮助伤口愈合的方法

 

Ever since I was a young girl, I was always fascinated -- 我从小就非常好奇—— (Laughter) (笑声) Oh! 哦! (Laughter) (笑声) OK, I meant younger and more short. 好吧,我是说更年轻,更矮的时候。 (Laughter) (笑声) If that's possible to imagine. 如果你可以想象到的话。 But ever since I was a young girl, 从我还是个小姑娘的时候开始, I was always fascinated with how the world worked exactly how it did. 我就对这个世界 是如何运转感到非常好奇。 So this, very early on, 这一点让我从很早开始, led me to the fields of mathematics and chemistry. 就对数学和化学很感兴趣。 I would keep going further and further, and as I kept going, 我努力学习,而随着学习的深入, I realized that all the fields of science are interconnected. 我意识到所有科学领域 都是互相关联的。 And without one, the others have little or no value. 如果离开某一学科,其他的学科的价值 就会大大下降,甚至毫无价值。 So, inspired by Marie Curie and my local science museum, 于是,受居里夫人 和我老家的科学博物馆的启发, I decided to start asking these questions myself 我决定开始在我家的车库里, 或者我的卧室中 and engage in my own independent research, 思考这些问题, whether it be out of my garage or my bedroom. 并进行独立研究。 I started reading journal papers, 我开始阅读期刊论文, started doing science competitions, 参加科学竞赛, started participating in science fairs, 参加科学展会, doing anything I could 用尽一切办法 to get the knowledge that I so desperately wanted. 获取我渴望的知识。 So while I was studying anatomy for a competition, 有一次为了参加竞赛, 我开始研究解剖学, I came across the topic of something called chronic wounds. 我遇到了一个名词, 叫长期性伤口。 And one thing that stood out to me was a statistic 引起我注意的是一项数据统计, that said that the number of people in the United States with chronic wounds 在美国有长期性伤口的人数 exceeds the number of people with breast cancer, 比患乳腺癌, colon cancer, lung cancer and leukemia, combined. 结肠癌、肺癌和白血病的人 加起来还多。 Hold up. 先等一下。 So what is a chronic wound? 什么是长期性伤口呢? (Laughter) (笑声) And why haven't I heard about a 5K walk for chronic wounds, 我怎么从没听过为支持 长期性伤口患者进行的5公里步行活动, why haven't I even heard about a chronic wound in general? 甚至从没听过长期性伤口这回事? (Laughter) (笑声) So after I got past those preliminary questions, 在我搞清楚这些初级问题之后, and one that I will clarify for you, 我要说清楚一点, a chronic wound is essentially when someone gets a normal wound, 长期性伤口本质上就是普通的伤口, except it fails to heal normally 只是它无法正常愈合, because the patient has some kind of preexisting condition, 因为病人在受伤之前 就已经有其他病症会影响愈合, which in most cases is diabetes. 大部分情况是糖尿病。 So more staggering statistics were to be found 随着研究的不断深入, as I kept going on in this research. 我找到了更多令人震惊的数据。 In the year 2010 alone, 仅在2010年, 50 billion dollars were spent worldwide to treat chronic wounds. 全球范围内用于治疗长期性伤口的 费用就高达500亿美元。 In addition, it's estimated that about two percent of the population 除此之外,据估计,有2%的人口 will get a chronic wound at some point in their lifetime. 会在一生中的某个时刻 遭遇长期性伤口。 This was absurd. 这真的有点难以置信。 So as I started doing more research, 于是我开始更深入的研究, I found that there was a correlation 我发现长期性伤口的出现与否 between the moisture level inside a wound dressing 与伤口包扎物的潮湿程度 and the stage of healing that the chronic wound would be at. 和伤口治疗所处的 阶段之间存在关联。 So I decided, why don't I design something 于是我就想, 为什么不设计一件产品, to measure the moisture level within the wound 可以测量伤口的湿度, so this can help doctors and patients treat their wounds better. 就能让医生和病人 更好地对伤口进行治疗。 And essentially, expedite the healing process. 这样一来就能加快治疗进程。 So that's exactly what I set out to do. 这就是我决定要做的事情。 Being a 14-year-old working out of her garage-turned-lab, 一个14岁女孩, 在自己家的车库实验室工作, I had a lot of constraints. 面临着许多限制。 Most being that I wasn't given a grant, I wasn't given a lot of money, 最主要的是我没有经费,没什么钱, and I wasn't given a lot of resources. 也没有什么资源。 In addition, I had a lot of criteria, as well. 除此之外,我的设计 还需要符合许多标准。 Since this product would be readily interacting with the body, 因为这个产品需要跟人体发生作用, it had to be biocompatible, 因此它必须具备生物兼容性, it also had to be low-cost, 而且成本要低, as I was designing it and paying for it myself. 因为我是自己设计并自费生产。 It also had to be mass-manufacturable, 而且它还需要能够量产, because I wanted it to be made anywhere, for anyone. 因为我想让它能 在任何地方生产,人人都能使用。 Thus, I drafted up a schematic. 因此,我画了个示意图。 What you see on the left hand-side is the early schematics in my design, 左手边的图是我早期的设计, showing both a bird's-eye view and also one stacking variant. 同时显示了鸟瞰图和堆叠变体。 A stacking variant means 堆叠变体的意思是, that the entire product is consisted of different individual parts 整个产品由不同的独立部分组成 that have to work in unison. 需要协同发挥作用。 And what's shown there is one possible arrangement. 图上显示的是某种可行的方案。 So what exactly is this? 那这些到底是什么呢? So I had gone on to testing my sensors 我对我的传感器进行了实验, and as all scientists have stumbles along their work, 但凡科学家,总会遇到挫折, I also had a couple of problems in my first generation of sensors. 我也不例外,第一代 传感器出现了不少问题。 First of all, I couldn't figure out 首先,我想不出好办法 how to get a nanoparticle ink into a printcheck cartridge 把纳米墨水精确地 注入打印墨盒里面, without spilling it all over my carpet. 而不会撒得地毯上到处都是。 That was problem number one. 这是第一个问题。 Problem number two was, 第二个问题, I couldn't exactly control the sensitivity of my sensors. 我没法控制传感器的灵敏度。 I couldn't scale them up or down, 无法将它调高或者调低, I couldn't really do anything of that sort. 一点办法都没有。 So I wanted something to solve it. 我要想办法解决问题。 Problem one was easily solved by some scouting on eBay and Amazon 第一个问题很容易, 我搜了一下易趣网和亚马逊, for syringes that I could use. 找到了我可以用的注射器。 Problem two, however, required a lot more thought. 第二个问题就需要 更多的思考来解决了。 So this is where this factors in. 下面就是我要谈的。 So what a space-filling curve does 所谓的空间填充曲线, is it aims to take up all the area it can within one unit square. 其目标是占据一个 平方单位内所有的空间。 And by writing a computer program, you can have different iterations 通过编写计算机程序, 你可以得到以不同方式重复的 of the different curve, 不同曲线, which increasingly get close to one unit square, 它们会越来越接近 填满一个平方单位, but never quite reaches there. 但永远也无法完全填满。 So now I could control the thickness, the size, 于是我就可以控制它的厚度、尺寸, I could do whatever I want with it, and I could predict my results. 做我想做的一切, 也可以对结果进行预测。 So I started constructing my sensors 于是我开始制造我的传感器 and testing them more rigorously, 并且更严格地测试, using money that I had gotten from previous science fair awards. 实验花费来自我以前 参加科学展会的奖金。 Lastly, I had to connect this data in order to be read. 最后,我需要建立输出,让数据可读。 So I interfaced it with a Bluetooth chip, 于是我用蓝牙芯片做了个交互界面, which you can see here by the app screenshots on the right. 就是右边的应用截屏的样子。 And what this does is that anyone can monitor the progress of their wound, 它可以让我们 监控自己伤口愈合的过程, and it can be transmitted over a wireless connection 也可以通过无线连接的方式 to the doctor, the patient or whoever needs it. 传给医生、病人或者任何需要的人。 [Continued Testing and Refinement] 【持续测试和改进中】 So in conclusion, my design was successful -- 总结来说,我的设计是成功的, however, science never ends. 当然,科学永无止尽。 There's always something to be done, something to be refined. 总有事情可以做,总有地方可以改进。 So that's what I'm currently in the process of doing. 这就是我现在正在做的。 However, what I learned was 然而,我真正学到的是 what's more important than the actual thing I designed 比起我设计出来的东西,更重要的 is an attitude that I had taken on while doing this. 是我在这过程中所持的态度。 And that attitude was, 这个态度就是, even though I'm a 14-year-old working in her garage 尽管我是一个14岁的孩子, 在自己家的车库中工作, on something that she doesn't completely understand, 做的也是自己不完全懂的事情, I could still make a difference and contribute to the field. 但我还是能做出点成绩, 对这个领域有所贡献。 And that's what inspired me to keep going, 这一点鼓励我继续前进, and I hope it inspires many others to also do work like this 我也希望能鼓励更多的人 来做同样的事情, even though they're not very sure about it. 尽管他们对此还不太确定。 So I hope that's a message that you all take on today. 这就是我今天想 传递给大家的信息。 Thank you. 谢谢大家。 (Applause) (掌声)

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